The Luca Lab

03/06/2025 & 05/30/2025: Our first two PhD students, Elliot Medina and Srishti Singh, are awarded their PhDs!!!
(Elliot pictured with ceremonial PhD sword)















04/24/2025: Srishti publishes her work on the engineering CD112-targeting biologics in Molecular Therapy!
Article: https://www.sciencedirect.com/science/article/abs/pii/S1525001625003119


10/02/2024: David's preprint on soluble Notch agonists is featured in Nature!  
Nature technology feature: https://www.nature.com/articles/d41586-024-03822-3
Link to preprint: www.biorxiv.org/content/10.1101/2024.08.06.606897v3


08/29/2024: Qianqian publishes the first structure of a LAG3-MHC class II complex!  
Article: https://www.nature.com/articles/s41467-024-51930-5


02/16/2023: Our review on Notch signaling biotechnologies was published in Trends in Pharmacological Sciences. 
Article: https://linkinghub.elsevier.com/retrieve/pii/S0165-6147(23)00213-4


02/16/2023: Elliot's paper on the tumor suppressor cadherins Fat4 & Dachsous1 was published in Nature Communications. 
Article: https://www.nature.com/articles/s41467-023-36435-x


06/29/2022: Qianqian's paper on the structure of LAG3 was published in Nature Immunology. 
Article: https://www.nature.com/articles/s41590-022-01238-7
News & Views article by Dr. Jamie Rossjohn: https://www.nature.com/articles/s41590-022-01239-6
Research briefing: https://www.nature.com/articles/s41590-022-01242-x


03/14/2022: David's paper on the high-affinity Notch ligand "DeltaMAX" was published in Nature Chemical Biology.
Article:https://www.nature.com/articles/s41589-022-01113-4