Welcome to the Luca Lab!

Our team uses structure-guided engineering to design novel proteins for biomedical applications.  Surface receptors sense environmental cues and relay signals that alter cellular behavior. By visualizing how immune cells send and receive information at the atomic level, our goal is to guide the development of next-generation immunotherapies.


We are happy to receive inquiries from highly motivated undergraduates, graduate students, and postdocs who are interested in working in the lab. Please send an e-mail to Vince.Luca@moffitt.org or see opportunities for more information.


Luca Lab team photo - April 2022