Welcome to the Luca Lab!

To orchestrate complex biological behaviors, cells sense cues from their local environment and relay signals to their neighbors. We study the "molecular language" of cell-to-cell communication using cutting edge approaches in structural, cellular and synthetic biology. Our goal is to visualize how cells send and receive information at the atomic level, and to harness this insight to guide the engineering of next-generation cancer therapeutics.


We are happy to receive inquiries from highly motivated undergraduates, graduate students and postdocs who are interested in working in the lab. Please send an e-mail to Vince.Luca@moffitt.org or see opportunities for more information.

'Molecular tension' strengthens Notch-ligand interactions 

Image courtesy of Eric Smith

The Luca Lab

Department of Drug Discovery

Stabile Research Building (3rd floor)

12902 Magnolia Dr, Tampa, FL 33612



Admin: 813-745-1425

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